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59 Biochemical properties of the histamine H3 receptor M. Apply an artery forceps to clamp the lateral canthus for a few seconds to produce haemostasis (fig. Familial cases appear to be autosomal dominant (50 of offspring inherit) The retinoblastoma (RB) gene actually is recessive at the molecular level; Normal individuals have two functional copies of the RB gene (RB, RB) Familial cases are heterozygous for retinoblastoma gene (RB, rb) Tumors develops when both normal genes in a single retinal cell are lost or inactivated.

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